Antidepressant and synaptic remodeling by cell adhesion molecules
نویسندگان
چکیده
منابع مشابه
Synaptic adhesion molecules and excitatory synaptic transmission
Synaptic adhesion molecules have been extensively studied for their contribution to the regulation of synapse development through trans-synaptic adhesions. However, accumulating evidence increasingly indicates that synaptic adhesion molecules are also involved in the regulation of excitatory synaptic transmission and plasticity, often through direct or close associations with excitatory neurotr...
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Synopsis The chemical synapse is a specialized asymmetric adhesion site between the axon of a neuron and its target cell. Synapse formation is a multi-step process involving target recognition followed by reciprocal inductive interactions that result in recruitment of proteins, such as receptors, and organelles, such as synaptic vesicles, to both the presynaptic and postsynaptic compartments. S...
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Polymorphic adhesion molecules neurexin and neuroligin (NL) mediate asymmetric trans-synaptic adhesion, which is crucial for synapse development and function. It is not known whether or how individual synapse function is controlled by the interactions between variants and isoforms of these molecules with differing ectodomain regions. At a physiological concentration of Ca(2+), the ectodomain co...
متن کاملIntroduction: Cell adhesion and extracellular matrix molecules in synaptic plasticity
This issue of Neuron Glia Biology contains a special collection of original research papers and reviews on the role of cell adhesion and extracellular matrix (ECM) molecules in synaptic plasticity. These molecules are crucially required for building and maintaining synaptic structure during brain development and there is increasing evidence that they also play important roles in modulating dist...
متن کاملIntroduction: Cell adhesion and extracellular matrix molecules in synaptic plasticity.
This issue of Neuron Glia Biology contains a special collection of original research papers and reviews on the role of cell adhesion and extracellular matrix (ECM) molecules in synaptic plasticity. These molecules are crucially required for building and maintaining synaptic structure during brain development and there is increasing evidence that they also play important roles in modulating dist...
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ژورنال
عنوان ژورنال: Folia Pharmacologica Japonica
سال: 2013
ISSN: 0015-5691,1347-8397
DOI: 10.1254/fpj.142.112